Understanding the experiences of people in HIV cure trials who pause their treatment.
Investigating Psychosocial Experiences of HIV Cure Trial Participants Undergoing Extended HIV Treatment Interruptions: Implications for Ethical Conduct
This study is looking to understand how people living with HIV feel about taking a break from their usual treatment while participating in clinical trials, so we can make the process better and more supportive for future participants.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10888271 on NIH RePORTER |
What this research studies
This research investigates the psychosocial experiences of individuals living with HIV who participate in clinical trials that require them to temporarily stop their antiretroviral treatment. The study focuses on understanding how these participants perceive the risks and benefits of this treatment interruption, known as an analytical treatment interruption (ATI). By gathering data from participants across multiple trials, the research aims to improve the informed consent process and address ethical challenges associated with HIV cure research. Participants will share their experiences and insights, which will help shape future studies and ethical guidelines.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who have achieved viral suppression and are considering participation in HIV cure trials involving treatment interruptions.
Not a fit: Patients who are not living with HIV or those who are not eligible for HIV cure trials may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the ethical conduct of HIV cure trials and improve the experiences of participants.
How similar studies have performed: Previous research has shown that understanding participant experiences in clinical trials can lead to improved ethical practices and participant satisfaction, indicating that this approach has potential for success.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Sauceda, John Andrew — University of California, San Francisco
- Study coordinator: Sauceda, John Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.