NIH-funded research R01 grant

Understanding the Ethics of HIV Studies for Young People in Africa

Official title: Ethics of HIV-related research involving underage key populations in sub-Saharan Africa

Funded at Suny Downstate Medical Center · NIH-11181027 · Data updated 2026-11-12

This project aims to understand and overcome challenges in including young people at high risk for HIV in health studies in sub-Saharan Africa.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSuny Downstate Medical Center
NIH-funded
Lab location1 site (Brooklyn, United States)
Project startSeptember 20, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$665,635
NIH project number5R01HD105684-05
Project IDNIH-11181027 on NIH RePORTER

Who could benefit from this research

Could help

This work is relevant to young people in sub-Saharan Africa who are at high risk for HIV and who might be interested in participating in future health studies.

Less likely to help

Patients who are not in sub-Saharan Africa or who are not part of the specific underage key populations at high risk for HIV may not directly benefit from this particular ethics project.

What this research studies

Many young people in sub-Saharan Africa, including those who sell sex or are adolescent men who have sex with men, face a high risk of HIV and other health issues. However, current rules often prevent them from joining health studies, especially due to difficulties in getting parental consent for sensitive topics. This project will look at the laws and ethical guidelines in 48 sub-Saharan African countries to see how they affect research with these young people. By identifying these barriers, the goal is to find better ways to include these vulnerable youth in future HIV prevention and treatment studies.

Why it matters

Potential benefit: This work could help ensure that future HIV prevention and treatment strategies are developed specifically for and with young people who are currently excluded from such important health studies.

How similar studies have gone: While the specific ethical and legal landscape is unique, other efforts have successfully adapted research protocols to include vulnerable populations, suggesting that overcoming these barriers is achievable.

Where this research is happening

  • Suny Downstate Medical Center
    Brooklyn, United States
    Active

Researchers

  • Principal investigator: Grosso, Ashley Lynn — Suny Downstate Medical Center
  • Study coordinator: Grosso, Ashley Lynn

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.