Understanding the effects of viral infections on inflammation and immunity
Official title: Viral Infection and Inflammation Workshop 2024
Funded at Brigham and Women's Hospital · NIH-10997471 · Data updated 2026-11-12
This study is looking at how viruses like COVID-19 and HIV impact the immune system and cause inflammation, especially in people dealing with long COVID and chronic fatigue syndrome, to find better treatments that can help improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 17, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $7,000 |
| NIH project number | 1R13AI186262-01 |
| Project ID | NIH-10997471 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing long COVID, chronic fatigue syndrome, or other post-viral syndromes.
✕Less likely to help
Patients with acute viral infections who do not experience long-term effects may not benefit from this research.
What this research studies
This research investigates how viral infections, such as COVID-19 and HIV, affect the immune system and lead to inflammation and autoimmune responses. It aims to explore the similarities and differences in the immune-mediated damage caused by these viruses, particularly in conditions like long COVID and chronic fatigue syndrome. The study will evaluate potential therapeutic interventions, including antiviral drugs and anti-inflammatory treatments, to improve patient outcomes. By analyzing the immune responses, the research seeks to identify effective strategies for managing post-viral syndromes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from long-term effects of viral infections.
How similar studies have gone: Previous research has shown promise in understanding immune responses to viral infections, indicating potential for success in this area.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Kuritzkes, Daniel R. — Brigham and Women's Hospital
- Study coordinator: Kuritzkes, Daniel R.
Related research
Other NIH-funded projects on the same topics.
-
Amyloid and HIV: How aging with HIV shapes Alzheimer’s disease at the cellular level
Researchers are studying how aging people with HIV accumulate Alzheimer’s–related brain changes, to understand who might benefit from future therapies.
-
Placental responses to maternal viral infection shape sex-specific offspring immunity
A mother’s viral infection during pregnancy can change how her baby’s immune system develops, potentially making some babies more prone to infections after birth.
-
Gut bacteria and lung immune cells shape viral lung infections
A study explores how gut microbes affect lung immune cells and severity of respiratory viral infections to identify potential ways to reduce illness.
-
Restoring helper CD4 T cells to help control chronic viral infections
A research project tests a strategy to revive CD4 Th1 helper T cells to better control chronic viral infections like HIV and hepatitis B/C in people who need improved immune control.
-
Screening small medicines to block RSV in baby and adult airway cells
A small study tests whether certain drugs can block age-related signals in respiratory cells to stop RSV infection in infants and young children.
-
Immune drivers of long-term lung damage after viral infection
Researchers are studying why some people’s lungs stay damaged after severe viral infections like COVID-19 and how to stop this scarring from getting worse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.