Understanding the effects of using opioids and stimulants together

Exploration of the unique neurobehavioral profile of sequential opioid-stimulant polysubstance use disorders

NIH-funded research University of Washington · NIH-11046497

This study is looking at how using opioids and stimulants like methamphetamine together affects behavior and addiction, and it's designed to help people who are dealing with addiction to multiple substances.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11046497 on NIH RePORTER

What this research studies

This research investigates the neurobehavioral effects of using opioids and stimulants, such as methamphetamine, together. It aims to understand how these substances interact in the brain and influence addiction behaviors. By studying a rodent model, researchers will define the behavioral profile associated with dual substance use, which could lead to the development of targeted treatments for those struggling with polysubstance addiction. The findings may provide insights into the unique neurobiological changes that occur with this combination of drugs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have a history of opioid and stimulant use disorders.

Not a fit: Patients who only use one type of substance or do not have a history of substance use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for individuals suffering from polysubstance use disorders.

How similar studies have performed: While research on polysubstance use is ongoing, this specific investigation into the dual effects of opioids and stimulants is relatively novel and untested.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.