Understanding the effects of using opioids and stimulants together
Official title: Exploration of the unique neurobehavioral profile of sequential opioid-stimulant polysubstance use disorders
Funded at University of Washington · NIH-11046497 · Data updated 2026-11-12
This study is looking at how using opioids and stimulants like methamphetamine together affects behavior and addiction, and it's designed to help people who are dealing with addiction to multiple substances.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $45,255 |
| NIH project number | 5F31DA059262-02 |
| Project ID | NIH-11046497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have a history of opioid and stimulant use disorders.
✕Less likely to help
Patients who only use one type of substance or do not have a history of substance use disorders may not benefit from this research.
What this research studies
This research investigates the neurobehavioral effects of using opioids and stimulants, such as methamphetamine, together. It aims to understand how these substances interact in the brain and influence addiction behaviors. By studying a rodent model, researchers will define the behavioral profile associated with dual substance use, which could lead to the development of targeted treatments for those struggling with polysubstance addiction. The findings may provide insights into the unique neurobiological changes that occur with this combination of drugs.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for individuals suffering from polysubstance use disorders.
How similar studies have gone: While research on polysubstance use is ongoing, this specific investigation into the dual effects of opioids and stimulants is relatively novel and untested.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Saavedra, Sara — University of Washington
- Study coordinator: Saavedra, Sara
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.