Understanding the effects of the 15q13.3 deletion syndrome on neuropsychiatric disorders
Elucidating the full phenotype of the 15q13.3 deletion syndrome
This study is looking at a genetic condition called 15q13.3 deletion syndrome to understand how it might be linked to different mental health issues, like autism and bipolar disorder, by gathering health information from 200 people with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10949087 on NIH RePORTER |
What this research studies
This research investigates the 15q13.3 deletion syndrome, a genetic condition that may increase the risk of neuropsychiatric disorders such as autism spectrum disorder and intellectual developmental disorder. By analyzing a cohort of 200 individuals with this deletion, the study aims to explore the full range of symptoms and conditions associated with it, including later-onset disorders like bipolar disorder and schizophrenia. The research will utilize electronic health records to gather comprehensive data on the participants' health and neurobehavioral traits. This approach seeks to better characterize the impact of this genetic variant on various medical and neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with the 15q13.3 deletion syndrome, particularly those experiencing neuropsychiatric symptoms.
Not a fit: Patients without the 15q13.3 deletion syndrome or those not exhibiting neuropsychiatric symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of neuropsychiatric disorders linked to the 15q13.3 deletion syndrome.
How similar studies have performed: Previous research has shown promise in understanding the implications of copy number variants on neuropsychiatric disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Soda, Takahiro — University of Florida
- Study coordinator: Soda, Takahiro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.