Understanding the effects of stopping malaria prevention in young children in Mali

"Investigating the rebound effects of seasonal malaria chemoprevention (SMC) in Mali"

NIH-funded research Univ of Sciences, Tech & Tech of Bamako · NIH-10898673

This study looks at how stopping a special malaria prevention treatment for young children in Mali affects the number of malaria cases, helping us understand what works best to keep kids healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of Sciences, Tech & Tech of Bamako NIH-funded
Lab location1 site (Bamako, Mali)
Project IDNIH-10898673 on NIH RePORTER

What this research studies

This research investigates the impact of seasonal malaria chemoprevention (SMC) on children under five years old in Mali. It focuses on how stopping SMC due to age restrictions affects malaria rates in both compliant and non-compliant children. By enrolling a large cohort, the study aims to compare malaria occurrences between those who received the full treatment and those who did not. The findings could help improve malaria prevention strategies in the region.

Who could benefit from this research

Good fit: Ideal candidates for this research are children under five years old who have participated in the seasonal malaria chemoprevention program.

Not a fit: Children over five years old or those who have not participated in the SMC program may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better malaria prevention strategies that protect children from severe malaria infections.

How similar studies have performed: Previous studies have shown significant decreases in malaria cases with SMC, but this research aims to explore the less understood rebound effects, making it a novel investigation.

Where this research is happening

Bamako, Mali

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.