NIH-funded research R01 grant

Understanding the effects of PFAS in drinking water on children's immune health

Official title: Assessment of pediatric immunotoxicity, public education, and capacity-building in communities impacted by PFAS-contaminated drinking water

Funded at Silent Spring Institute · NIH-10436901 · Data updated 2026-11-12

This study is looking at how certain chemicals in drinking water, called PFAS, might affect the immune health of children in communities that have been exposed to these substances, especially from firefighting foams, and it aims to create helpful resources to inform families about the health risks and options available to them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSilent Spring Institute
NIH-funded
Lab location1 site (Newton, United States)
Project startSeptember 7, 2018
Project endJune 30, 2025
Funding year2022
Award (this year)$514,966
NIH project number5R01ES028311-05
Project IDNIH-10436901 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include children living in communities with PFAS-contaminated drinking water.

Less likely to help

Patients who do not reside in areas affected by PFAS contamination may not benefit from this research.

What this research studies

This research investigates the impact of per- and polyfluoroalkyl substances (PFAS) found in drinking water on the immune health of children. It focuses on communities affected by PFAS contamination, particularly those exposed to firefighting foams. The study will assess immune responses in young children and develop educational resources to help communities understand health risks and treatment options. By collaborating with local communities, the project aims to provide valuable information and support for those impacted by PFAS.

Why it matters

Potential benefit: If successful, this research could lead to improved health guidelines and protective measures for children exposed to PFAS in drinking water.

How similar studies have gone: Previous studies have indicated potential health risks associated with PFAS exposure, suggesting that this research builds on established findings rather than being entirely novel.

Where this research is happening

  • Silent Spring Institute
    Newton, United States
    Active

Researchers

  • Principal investigator: Schaider, Laurel a. — Silent Spring Institute
  • Study coordinator: Schaider, Laurel a.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.