Understanding the effects of non-dysentery Shigella diarrhea in children
The impact of non-dysentery Shigella-associated diarrhea in children
This study is looking at how a type of bacteria that causes watery diarrhea in kids affects their health, especially in poorer areas, and it aims to find a quick test to help doctors treat these infections faster, so children can get better sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11037892 on NIH RePORTER |
What this research studies
This research investigates the impact of non-dysentery Shigella infections, which cause watery diarrhea in children, particularly in impoverished areas. The study aims to identify these infections quickly using a rapid diagnostic test, allowing for timely antibiotic treatment that could improve survival and long-term health outcomes. By comparing children with non-dysentery Shigella to those with dysentery, the research seeks to better understand the severity and implications of these infections. The study will be conducted in a hospital setting in Bangladesh, focusing on children under 12 years old.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 12 years old who are experiencing diarrhea and are seeking care in a hospital setting.
Not a fit: Patients who do not have diarrhea or are older than 12 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols for children suffering from non-dysentery Shigella infections, potentially saving lives and enhancing developmental outcomes.
How similar studies have performed: Previous research has shown that timely identification and treatment of bacterial infections can significantly improve patient outcomes, suggesting a promising avenue for this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Chakraborty, Subhra — Johns Hopkins University
- Study coordinator: Chakraborty, Subhra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.