Understanding the effects of auditory nerve loss on hearing
Behavioral and physiological consequences of auditory nerve loss
This study is looking at how losing tiny nerve fibers in the ear affects hearing, especially as we get older or are around loud noises, using budgerigars to help understand why some people have trouble hearing in noisy places even when regular tests say their hearing is fine.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10877433 on NIH RePORTER |
What this research studies
This research investigates how the loss of auditory nerve fibers affects hearing, particularly in the context of aging and exposure to loud sounds. Using budgerigars as a model, the study aims to explore the mechanisms behind 'hidden' hearing difficulties that may not show up in standard hearing tests. Through behavioral experiments and neural recordings, researchers will assess how these changes impact the perception of sounds, especially in noisy environments. The findings could provide insights into the underlying causes of hearing difficulties that many people experience as they age.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing hearing difficulties, particularly those who have been exposed to loud sounds or are aging.
Not a fit: Patients with normal hearing thresholds and no history of auditory nerve damage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals experiencing hidden hearing loss.
How similar studies have performed: While this approach is innovative, previous studies have shown promise in using animal models to understand auditory processing and related conditions.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Henry, Kenneth Stuart — University of Rochester
- Study coordinator: Henry, Kenneth Stuart
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.