Understanding the diversity of brain cells that regulate information flow
Official title: Molecular Mechanisms of Somatostatin Interneuron Diversity
Funded at Harvard Medical School · NIH-11013932 · Data updated 2026-11-12
This study is looking at special brain cells called somatostatin interneurons to understand how they help process information, which could help us learn more about how the brain works and what makes these cells unique.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $34,444 |
| NIH project number | 5F31NS130915-03 |
| Project ID | NIH-11013932 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older who may have conditions related to brain function or neurological disorders.
✕Less likely to help
Patients with acute neurological injuries or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the different types of somatostatin interneurons in the brain, which play a crucial role in controlling how information is processed. By examining the genetic and developmental factors that contribute to the diversity of these cells, the research aims to uncover the mechanisms behind their unique properties. The study will utilize advanced techniques to analyze the transcriptomic and epigenetic changes that occur during the development of these interneurons. This could provide insights into how these cells function in the adult brain and their impact on overall brain activity.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of brain function and potential new treatments for neurological disorders.
How similar studies have gone: Other research has shown promising results in understanding brain cell diversity, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Lee, Jinoh — Harvard Medical School
- Study coordinator: Lee, Jinoh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.