Understanding the diverse roles of neutrophils in health and disease
Non-canonical functions of neutrophils
This study is looking at how a type of white blood cell called neutrophils works in different parts of the body and how they can affect health issues like cancer and inflammation, with the goal of finding better ways to treat these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11090411 on NIH RePORTER |
What this research studies
This research investigates how neutrophils, a type of white blood cell, function in various tissues and their roles in both health and disease. It aims to explore how these immune cells adapt to different environments and how their behavior can influence conditions like cancer and inflammation. By examining the mechanisms that determine neutrophil functions, the research seeks to uncover their contributions to tissue health and the potential consequences of their dysfunction. This could lead to new insights into how to manage diseases associated with neutrophil activity.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with cancer or chronic inflammatory conditions who may be affected by neutrophil activity.
Not a fit: Patients with acute infections or those not experiencing any immune-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions related to neutrophil dysfunction, such as cancer and chronic inflammatory diseases.
How similar studies have performed: Previous research has shown promising results in understanding the roles of immune cells in disease, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Hidalgo, Andres — Yale University
- Study coordinator: Hidalgo, Andres
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.