Understanding the different types of fat cells in the human body
Investigating Human Adipocyte Heterogeneity
This study is looking at different types of fat cells in our bodies to see how they work and how they might be linked to conditions like diabetes, and it will also create a helpful online resource to share what we learn with others.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11094906 on NIH RePORTER |
What this research studies
This research investigates the various subpopulations of white adipocytes, which are fat cells that play a crucial role in energy storage and metabolic regulation. By utilizing advanced single nuclear sequencing techniques, the study aims to identify distinct types of these cells and understand their functions and development. The research will also explore how these adipocyte subpopulations relate to metabolic diseases, such as adult-onset diabetes. Additionally, a Human Adipose Tissue Knowledge Portal will be created to share findings and standardize data across research efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with metabolic disorders, particularly those related to obesity and diabetes.
Not a fit: Patients who do not have metabolic disorders or related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of metabolic diseases linked to fat cell diversity.
How similar studies have performed: Other research has shown promise in understanding adipocyte diversity, but this approach using advanced sequencing techniques is relatively novel.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Rosen, Evan D — Beth Israel Deaconess Medical Center
- Study coordinator: Rosen, Evan D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.