Understanding the different types of COPD using advanced technology
Linking endotype and phenotype to understand COPD heterogeneity via deep learning and network science
['FUNDING_CAREER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11001158
This study is looking at chronic obstructive pulmonary disease (COPD) to better understand the different ways it affects people, using advanced technology to create detailed profiles that could help doctors provide more personalized treatments and improve predictions about how the disease will progress.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11001158 on ClinicalTrials.gov |
What this research studies
This research investigates chronic obstructive pulmonary disease (COPD), a complex condition with varying symptoms and progression among patients. By utilizing deep learning and network science, the study aims to combine clinical and genomic data to create detailed patient profiles. These profiles will help identify distinct subtypes of COPD, which can lead to more personalized treatment options and better predictions of disease outcomes. The approach focuses on integrating various data types to enhance our understanding of the disease's heterogeneity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD) who exhibit a range of symptoms and disease progression.
Not a fit: Patients with mild or early-stage COPD who do not exhibit significant heterogeneity in their condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more tailored treatments for COPD patients, improving their quality of life and disease management.
How similar studies have performed: Previous research has shown promise in using advanced data integration techniques to classify complex diseases, suggesting that this approach could yield valuable insights for COPD as well.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAIORINO, ENRICO — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: MAIORINO, ENRICO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.