Understanding the different cell types in the outer layer of skin
Official title: Defining the heterogeneity of cell lineages in the inter-follicular epidermis
Funded at Cornell University · NIH-11042173 · Data updated 2026-11-12
This study is looking at how the outer layer of your skin stays healthy and renews itself by examining different types of skin cells and how they react to things like sun exposure, which could help us learn more about skin health and conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | April 12, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $447,043 |
| NIH project number | 5R01AR070157-08 |
| Project ID | NIH-11042173 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are interested in skin health and regeneration.
✕Less likely to help
Patients with conditions unrelated to skin health or those under 21 years old may not benefit from this research.
What this research studies
This research investigates how the outer layer of skin, known as the inter-follicular epidermis (IFE), is renewed and maintained by various types of cells. It aims to uncover the complex organization of these cells and their roles in responding to environmental factors like UV exposure. By using advanced techniques in mouse models, the study will explore how different cell populations behave and transition through stages of growth and maturation. This could lead to a better understanding of skin health and disease.
Why it matters
Potential benefit: If successful, this research could improve our understanding of skin regeneration and lead to better treatments for skin-related conditions.
How similar studies have gone: Other research has shown success in understanding skin cell behavior and regeneration, making this approach promising.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Tumbar, Tudorita — Cornell University
- Study coordinator: Tumbar, Tudorita
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.