Understanding the different causes and effects of ADHD in children

Parsing Neurobiological Bases of Heterogeneity in ADHD

['FUNDING_R01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10815752

This study is looking at how different brain factors affect the symptoms of ADHD in kids, using special tests to understand their attention better, so we can find more tailored treatments for them.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCINCINNATI CHILDRENS HOSP MED CTR (nih funded)
Locations1 site (CINCINNATI, UNITED STATES)
Trial IDNIH-10815752 on ClinicalTrials.gov

What this research studies

This research investigates the complex nature of Attention-Deficit/Hyperactivity Disorder (ADHD) in children by focusing on how various neurobiological factors contribute to the disorder's diverse symptoms. The study aims to move beyond traditional symptom assessments by utilizing clinically meaningful measures related to attention, specifically examining reaction time variability (RTV) as a key indicator. By analyzing data from the Adolescent Brain Cognitive Development (ABCD) study, which includes extensive neuroimaging and attentional tasks, researchers hope to uncover the underlying neurobiological mechanisms of ADHD and how they relate to the disorder's heterogeneity. This research could provide insights into more personalized treatment approaches for children with ADHD.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 9 to 10 who have been diagnosed with ADHD.

Not a fit: Patients who do not have ADHD or are outside the age range of 9 to 10 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for children with ADHD, tailored to their specific neurobiological profiles.

How similar studies have performed: Previous research has shown promise in using neurobiological measures to understand ADHD, but this specific approach is innovative and aims to deepen the understanding of the disorder's heterogeneity.

Where this research is happening

CINCINNATI, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Mental health disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.