Understanding the differences in behavior and brain function in OCD and depression
Behavioral and Neural Heterogeneity in OCD and Depression
This study is looking at how the brains and behaviors of people with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) are different and similar, with the hope of finding better ways to help those with these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10911805 on NIH RePORTER |
What this research studies
This research explores the varying behaviors and brain functions in individuals with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD). By using advanced imaging techniques like functional MRI, the study aims to identify how different symptoms relate to brain activity and psychological factors. The project will involve 150 participants, including 75 with OCD and 75 with MDD, to better understand the underlying causes of these conditions and improve treatment strategies. The goal is to find commonalities and differences that could lead to more personalized and effective interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with obsessive-compulsive disorder or major depressive disorder.
Not a fit: Patients with other mental health disorders or those not meeting the criteria for OCD or MDD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options tailored to the specific needs of patients with OCD and depression.
How similar studies have performed: Previous research has shown promise in understanding the neural and behavioral aspects of OCD and depression, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Stern, Emily R — New York University School of Medicine
- Study coordinator: Stern, Emily R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.