Understanding the differences between harmless and aggressive breast calcifications
Dynamic imaging and tissue biomarker models to delineate indolent from aggressive breast calcifications
This study is looking at how breast calcifications change over time to help doctors tell the difference between harmless and serious breast conditions, so patients can get more accurate screenings and avoid unnecessary procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10915643 on NIH RePORTER |
What this research studies
This research aims to improve breast cancer screening by analyzing the dynamic changes in breast calcifications over time. By utilizing advanced imaging techniques and tissue biomarkers, the study seeks to better differentiate between benign conditions and aggressive forms of breast cancer. Patients will benefit from a more accurate assessment of their breast health, potentially reducing unnecessary biopsies and overtreatment. The approach involves tracking calcification patterns through serial mammograms to inform clinical decision-making.
Who could benefit from this research
Good fit: Ideal candidates for this research are women undergoing routine breast cancer screening who have been identified with calcifications on mammograms.
Not a fit: Patients who do not have breast calcifications or those with advanced breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate breast cancer diagnoses and reduce the number of unnecessary procedures for patients.
How similar studies have performed: Previous research has shown promise in using dynamic imaging techniques to improve cancer detection, suggesting that this approach may yield significant advancements.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Grimm, Lars J — Duke University
- Study coordinator: Grimm, Lars J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.