Understanding the development of specific neurons in the amygdala during adolescence
Identity of late-maturing amygdala neurons in humans and mice
This study is looking at how specific brain cells in the amygdala grow and change during teenage years, using both people and mice, to help us understand how our emotions and social skills develop as we grow up.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11080247 on NIH RePORTER |
What this research studies
This research investigates how certain neurons in the amygdala, a brain region important for emotional and social development, mature during adolescence. By studying both humans and mice, the researchers aim to track the growth and integration of these neurons over time. They will use advanced techniques to observe the development of these neurons from their early formation in the embryo to their functional roles in the brain. This work could provide insights into how emotional and social behaviors develop during critical growth periods.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include adolescents aged 12-20 and adults who may have developmental concerns related to the amygdala.
Not a fit: Patients outside the age range of 12-20 or those without any developmental or emotional concerns may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential interventions for emotional and social development issues in adolescents.
How similar studies have performed: Other research has shown success in understanding neuronal development in animal models, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Sorrells, Shawn — University of Pittsburgh at Pittsburgh
- Study coordinator: Sorrells, Shawn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.