Understanding the development of bipolar I disorder in young people

1/2 Neurodevelopmental and clinical trajectories of youth at risk for bipolar I disorder

NIH-funded research University of Texas at Austin · NIH-11111169

This study is looking at how bipolar I disorder starts in young people, especially those with a family history of the condition, by exploring how genes and early life experiences might lead to symptoms like mania, with the goal of finding early warning signs and better ways to help them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-11111169 on NIH RePORTER

What this research studies

This research investigates how bipolar I disorder develops in youth, particularly focusing on those at risk due to family history. It examines the interplay between genetic factors and early life experiences that may contribute to the onset of mania, which often begins in adolescence. The study aims to identify early signs and symptoms, as well as the impact of environmental stressors on mental health. By tracking these factors over time, the research seeks to improve understanding and treatment of bipolar disorder in young individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents and young adults aged 12 to 21 with a family history of bipolar disorder or related psychiatric conditions.

Not a fit: Patients who do not have a family history of bipolar disorder or who are outside the age range of 12 to 21 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and intervention strategies for youth at risk of developing bipolar I disorder.

How similar studies have performed: Previous research has shown promising results in understanding the early indicators of bipolar disorder, suggesting that this approach could yield valuable insights.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.