Understanding the development of bipolar disorder in youth at risk

2/2-Neurodevelopmental and Clinical Trajectories of Youth at Risk for Bipolar Disorder

['FUNDING_R01'] · UNIVERSITY OF CINCINNATI · NIH-11092149

This study is looking at how bipolar disorder starts in teens and young adults who have family members with the condition, focusing on how their genes and early life experiences might play a role, so we can better understand what helps or hinders their mental health as they grow up.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CINCINNATI (nih funded)
Locations1 site (CINCINNATI, UNITED STATES)
Trial IDNIH-11092149 on ClinicalTrials.gov

What this research studies

This research investigates how bipolar disorder develops in adolescents and young adults who have a family history of the condition. It focuses on the interplay between genetic predispositions and early life experiences that may contribute to the onset of symptoms like mania. By examining brain development and behavioral patterns, the study aims to identify critical factors that influence the trajectory of bipolar disorder in at-risk youth. Participants may undergo assessments and follow-ups to track their mental health and development over time.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults aged 12 to 21 with a family history of bipolar disorder or related psychiatric conditions.

Not a fit: Patients without a family history of bipolar disorder or those who are not within the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early interventions and preventive strategies for young individuals at risk of developing bipolar disorder.

How similar studies have performed: Previous research has shown that understanding the early development of bipolar disorder can lead to significant advancements in treatment and prevention strategies.

Where this research is happening

CINCINNATI, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.