Understanding the Connection Between Lungs and Brain After Stroke
Lung-Brain Coupling and the Immune Response to Acute Ischemic Stroke
This project explores how the lungs and brain communicate after an acute stroke to find new ways to help patients recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-11143165 on NIH RePORTER |
What this research studies
After a stroke, the brain and immune system interact in ways that can worsen damage. We've found a new connection between the lungs and brain that influences the body's immune response and can lead to more brain damage. This work aims to understand how stroke affects the lungs and how these lung changes impact the brain. We are looking into whether protecting the lungs after a stroke could reduce inflammation and improve recovery for patients.
Who could benefit from this research
Good fit: Patients who have experienced an acute ischemic stroke might eventually benefit from the findings of this research.
Not a fit: Patients with other types of brain injuries or chronic conditions not related to acute ischemic stroke may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that target lung health after a stroke, potentially reducing inflammation and improving recovery for patients.
How similar studies have performed: This research explores a novel mechanism of lung-brain coupling after stroke, indicating a new and untested approach for targeted therapies.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Halterman, Marc W — State University of New York at Buffalo
- Study coordinator: Halterman, Marc W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.