Understanding the connection between delirium and dementia

Clarifying the overlapping pathology of delirium and dementia

NIH-funded research University of Wisconsin-Madison · NIH-11049433

This study is looking at how delirium and dementia are connected and how they affect the brain, with the hope of finding new ways to help people with dementia who are at risk for delirium.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-11049433 on NIH RePORTER

What this research studies

This research investigates the overlapping causes of delirium and dementia, two conditions that significantly impact cognitive function and quality of life. By measuring brain electrical activity and examining neurotransmitter changes, the study aims to clarify how these conditions are related and identify potential new therapies. Patients with dementia are particularly vulnerable to delirium, making this research crucial for understanding their shared pathology. The findings could lead to better treatment options for both conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with dementia who may also experience episodes of delirium.

Not a fit: Patients with cognitive impairments not related to dementia or delirium may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that improve cognitive function and quality of life for patients suffering from delirium and dementia.

How similar studies have performed: Previous research has shown promise in understanding the relationship between neurotransmitters and cognitive disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.