Understanding the common mechanisms behind different types of chronic pain
The conserved mechanisms underlying different types of chronic pain
This study is looking into how certain processes in the spinal cord can make chronic pain worse, with the hope of finding new ways to help people manage their pain better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10910097 on NIH RePORTER |
What this research studies
This research investigates the underlying mechanisms that contribute to various forms of chronic pain, focusing on how certain molecular processes in the spinal cord can lead to pain hypersensitivity. By examining the role of specific proteins and signaling pathways, the study aims to identify potential therapeutic targets that could help alleviate chronic pain. The approach involves detailed analysis of cellular changes in the spinal dorsal horn, which is a key area involved in pain processing. Patients may benefit from insights gained into how chronic pain develops and persists, potentially leading to new treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from various types of chronic pain, including those with conditions like neuropathic pain or pain resulting from injury.
Not a fit: Patients with acute pain or those whose pain is not chronic in nature may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively manage or reduce chronic pain for many patients.
How similar studies have performed: Previous research has shown promise in understanding chronic pain mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Li, Lingyong — University of Alabama at Birmingham
- Study coordinator: Li, Lingyong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.