NIH-funded research U01 cooperative agreement

Understanding the causes of type 2 diabetes in young people

Official title: Metabolic, behavioral and social determinants of youth-onset T2D

Funded at Albert Einstein College of Medicine · NIH-11054643 · Data updated 2026-11-12

This study is looking at how things like lifestyle, social situations, and health can affect kids in the Bronx who are at risk for type 2 diabetes, and it aims to find better ways to help them stay healthy.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine
NIH-funded
Lab location1 site (Bronx, United States)
Project startMarch 24, 2023
Project endJanuary 31, 2029
Funding year2025
Award (this year)$734,852
NIH project number5U01DK134988-03
Project IDNIH-11054643 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children and adolescents at risk for type 2 diabetes, particularly those from diverse racial and ethnic backgrounds living in areas with high rates of obesity and socioeconomic challenges.

Less likely to help

Patients who do not have risk factors for type 2 diabetes or who are not within the targeted age group may not benefit from this research.

What this research studies

This research investigates the metabolic, behavioral, and social factors that contribute to youth-onset type 2 diabetes (YT2D). By establishing a cohort of children at risk for YT2D from the Bronx, the study aims to explore how social determinants of health, such as economic and food insecurity, interact with biological factors to influence diabetes risk. Participants will be monitored using activity trackers and other assessments to gather comprehensive data on their health and lifestyle. The goal is to better understand the unique challenges faced by youth with diabetes and to identify effective prevention strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and management strategies for youth-onset type 2 diabetes, ultimately reducing its prevalence and complications.

How similar studies have gone: Previous research has shown success in understanding the impact of social determinants on health outcomes, making this approach both relevant and promising.

Where this research is happening

  • Albert Einstein College of Medicine
    Bronx, United States
    Active

Researchers

  • Principal investigator: Isasi, Carmen R. — Albert Einstein College of Medicine
  • Study coordinator: Isasi, Carmen R.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.