Understanding the causes of type 2 diabetes in children and adolescents
Cincinnati Children's Clinical Center for Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes
This study is looking for kids and teens who might be at risk for type 2 diabetes to help understand what causes the condition, so we can find better ways to prevent it in the future.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11051124 on NIH RePORTER |
What this research studies
This research investigates the underlying causes of youth-onset type 2 diabetes (T2D) by recruiting a cohort of children and adolescents who are at risk for developing this condition. Participants will undergo detailed assessments of their pancreatic function, insulin sensitivity, and various metabolic factors, alongside evaluations of their genetics and psychosocial behaviors. The goal is to identify how these factors contribute to the progression of T2D, ultimately aiming to improve prevention strategies for this aggressive disease.
Who could benefit from this research
Good fit: Ideal candidates for participation are children and adolescents who are at risk for developing type 2 diabetes, particularly those with obesity or a family history of diabetes.
Not a fit: Patients who are not at risk for type 2 diabetes or those who have already been diagnosed with the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for youth-onset type 2 diabetes, improving health outcomes for affected children and adolescents.
How similar studies have performed: Previous research has shown promise in understanding diabetes through similar observational cohort studies, indicating that this approach could yield valuable insights.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Shah, Amy Sanghavi — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Shah, Amy Sanghavi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.