NIH-funded research NIH-funded research

Understanding the causes of shaky voice in essential tremor patients

Official title: Differentiating the Physiological Sources of Modulated Voice

Funded at University of Texas at Austin · NIH-11143528 · Data updated 2026-11-12

This study is looking into why some people with essential tremor experience shaking in their voice, and it aims to find better ways to help them communicate more clearly.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$238,500
NIH project number1R56DC021972-01
Project IDNIH-11143528 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with essential tremor who experience vocal tremor affecting their speech.

Less likely to help

Patients without essential tremor or those whose vocal issues are unrelated to tremor may not benefit from this research.

What this research studies

This research investigates the physiological sources of vocal tremor in patients with essential tremor, a common movement disorder affecting millions. It aims to identify the specific subsystems of the voice that are impacted by tremors, using advanced clinical assessments that include nasolaryngoscopy. By pinpointing the exact causes of vocal tremor, the research seeks to improve treatment strategies and enhance communication for affected individuals. The study addresses the limitations of current management techniques, which often yield inconsistent results and do not target specific impairments.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with vocal tremor, significantly improving their quality of life and communication abilities.

How similar studies have gone: While there has been research on essential tremor, this specific approach to differentiating the physiological sources of vocal tremor is novel and has not been extensively tested.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Lester-Smith, Rosemary Anne — University of Texas at Austin
  • Study coordinator: Lester-Smith, Rosemary Anne

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.