Understanding the causes of rotator cuff tears in people

Investigating the Multi-factorial Etiology of Rotator Cuff Pathology in Human Subjects

NIH-funded research Washington University · NIH-10709899

This study is looking at what causes rotator cuff tears in older adults, focusing on how things like shoulder movement and tendon health play a role, so we can better understand this common shoulder problem.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10709899 on NIH RePORTER

What this research studies

This research investigates the various factors that contribute to rotator cuff tears, a common and painful shoulder condition affecting many older adults. The study aims to develop a model that identifies how extrinsic factors, like shoulder motion, and intrinsic factors, such as tendon degeneration, influence the development of these tears. By using advanced imaging techniques, researchers will assess both asymptomatic and symptomatic individuals to better understand the condition's etiology. This comprehensive approach seeks to clarify the complex interactions between different contributing factors.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals over the age of 60, particularly those who are asymptomatic or experiencing shoulder pain.

Not a fit: Patients with acute rotator cuff injuries or those under the age of 60 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for rotator cuff tears, enhancing the quality of life for affected patients.

How similar studies have performed: Previous research has shown success in understanding rotator cuff pathology through animal models, but this study aims to confirm these findings in human subjects, making it a novel approach.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.