Understanding the causes of non-immune hydrops fetalis through genetic analysis

Uncovering the etiologies of non-immune hydrops fetalis through comprehensive genomic analyses and phenotyping

NIH-funded research University of California, San Francisco · NIH-11020996

This study is looking into the genetic causes of non-immune hydrops fetalis (NIHF), a condition where extra fluid builds up in a baby during pregnancy, to help doctors provide better care for both moms and their babies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11020996 on NIH RePORTER

What this research studies

This research investigates non-immune hydrops fetalis (NIHF), a condition diagnosed during pregnancy when abnormal fluid accumulates in the fetus. By utilizing advanced genomic analyses and phenotyping, the study aims to identify the genetic causes of NIHF, which can significantly affect prenatal and postnatal care. The research will analyze genetic data from affected pregnancies to provide targeted management strategies, improving outcomes for both mothers and infants. The goal is to enhance the understanding of NIHF and implement timely interventions based on identified etiologies.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant individuals whose fetuses have been diagnosed with non-immune hydrops fetalis and for whom the cause remains unknown.

Not a fit: Patients whose non-immune hydrops fetalis has a known cause or those not diagnosed with this condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prenatal care and better health outcomes for infants diagnosed with non-immune hydrops fetalis.

How similar studies have performed: Previous research has shown success in identifying genetic causes of similar conditions, indicating that this approach has the potential for meaningful advancements.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.