Understanding the causes of low back pain flare-ups

What causes low back pain to flare: Has a major opportunity to understand back pain been missed?

NIH-funded research University of Queensland · NIH-10914077

This study is looking at what causes flare-ups of low back pain so we can better understand and help people who experience it by listening to their personal stories and triggers.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Queensland NIH-funded
Lab location1 site (Brisbane, Australia)
Project IDNIH-10914077 on NIH RePORTER

What this research studies

This research investigates the factors that lead to flare-ups of low back pain (LBP), which affects a significant number of individuals. It aims to identify the various transient and fluctuating exposures that contribute to these painful episodes, moving beyond traditional views of LBP as either acute or chronic. By utilizing innovative methods and technology, the study seeks to personalize care for patients by understanding their unique experiences and triggers for pain flares. The research involves collaboration with individuals suffering from LBP to gain insights into their perspectives on what causes these flare-ups.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing recurrent low back pain with episodes of increased symptoms.

Not a fit: Patients with low back pain that is stable and does not experience flare-ups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention strategies and personalized treatment options for individuals suffering from low back pain.

How similar studies have performed: While there has been research on low back pain, this approach focusing on the variability of flare-ups and personalized care is relatively novel.

Where this research is happening

Brisbane, Australia

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.