Understanding the causes of low back pain flare-ups
Official title: What causes low back pain to flare: Has a major opportunity to understand back pain been missed?
Funded at University of Queensland · NIH-10914077 · Data updated 2026-11-12
This study is looking at what causes flare-ups of low back pain so we can better understand and help people who experience it by listening to their personal stories and triggers.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Queensland NIH-funded |
| Lab location | 1 site (Brisbane, Australia) |
| Project start | September 22, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $427,561 |
| NIH project number | 5R01AR080354-03 |
| Project ID | NIH-10914077 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing recurrent low back pain with episodes of increased symptoms.
✕Less likely to help
Patients with low back pain that is stable and does not experience flare-ups may not benefit from this research.
What this research studies
This research investigates the factors that lead to flare-ups of low back pain (LBP), which affects a significant number of individuals. It aims to identify the various transient and fluctuating exposures that contribute to these painful episodes, moving beyond traditional views of LBP as either acute or chronic. By utilizing innovative methods and technology, the study seeks to personalize care for patients by understanding their unique experiences and triggers for pain flares. The research involves collaboration with individuals suffering from LBP to gain insights into their perspectives on what causes these flare-ups.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention strategies and personalized treatment options for individuals suffering from low back pain.
How similar studies have gone: While there has been research on low back pain, this approach focusing on the variability of flare-ups and personalized care is relatively novel.
Where this research is happening
-
University of Queensland
Brisbane, Australia Active
Researchers
- Principal investigator: Klyne, David M — University of Queensland
- Study coordinator: Klyne, David M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.