Understanding the causes of knee pain in older adults
Biobehavioral basis of knee osteoarthritis pain
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10793573
This study is looking at how different biological and lifestyle factors affect knee pain in older adults with osteoarthritis, and it aims to find clues that could help predict pain and its impact on overall health, while including both Black and White participants to see how experiences might differ across these groups over four years.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10793573 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between knee osteoarthritis pain and various biological and behavioral factors in older adults. It aims to identify biomarkers that can predict pain and its effects on physical and mental health over time. By studying both non-Hispanic Black and non-Hispanic White individuals, the research seeks to understand how different factors influence pain experiences across diverse racial and ethnic groups. Participants will be monitored over four years to gather comprehensive data on their pain levels and related health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged and older adults experiencing knee pain, particularly those who identify as non-Hispanic Black or non-Hispanic White.
Not a fit: Patients who do not have knee pain or are younger than middle age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of personalized, non-opioid treatments for knee pain that improve overall health outcomes for older adults.
How similar studies have performed: Previous research has shown promise in using biomarkers to predict pain and health outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CRUZ-ALMEIDA, YENISEL — UNIVERSITY OF FLORIDA
- Study coordinator: CRUZ-ALMEIDA, YENISEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.