Understanding the causes of internalizing disorders in a large population cohort
An Integrative Approach to the Etiology of Internalizing Disorders in the Lifelines Cohort
This study is looking at what causes and affects depression and anxiety in adults in the Netherlands by checking in with participants every five years to see how their experiences and backgrounds influence their mental health over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10976426 on NIH RePORTER |
What this research studies
This research investigates the underlying causes and progression of internalizing disorders, such as depression and anxiety, by analyzing data from a large cohort of adults in the Netherlands. The study utilizes a comprehensive approach, examining genetic, environmental, and familial factors that contribute to these disorders. Participants will be assessed every five years, allowing researchers to track changes and comorbidities over time. The goal is to identify shared and specific mechanisms that lead to these mental health conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults experiencing symptoms of internalizing disorders, such as depression or anxiety.
Not a fit: Patients with solely physical health issues unrelated to mental health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals suffering from internalizing disorders.
How similar studies have performed: Previous research has shown promise in understanding the etiology of mental health disorders using similar integrative approaches.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Kendler, Kenneth Seedman — Virginia Commonwealth University
- Study coordinator: Kendler, Kenneth Seedman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.