Understanding the causes of hereditary pancreatitis
Mechanisms of Hereditary Pancreatitis
['FUNDING_R01'] · MAYO CLINIC JACKSONVILLE · NIH-11031380
This study is looking at hereditary pancreatitis, a genetic condition that can cause painful flare-ups and serious complications, using a special mouse model to better understand how it works and find new ways to treat it.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC JACKSONVILLE (nih funded) |
| Locations | 1 site (JACKSONVILLE, UNITED STATES) |
| Trial ID | NIH-11031380 on ClinicalTrials.gov |
What this research studies
This research investigates hereditary pancreatitis, a genetic condition that leads to recurrent episodes of acute pancreatitis and can progress to chronic pancreatitis and pancreatic cancer. The team has developed a novel mouse model that mimics the human condition, allowing them to study the disease mechanisms in detail. By examining how specific genetic mutations and enzyme levels affect the disease, they aim to uncover potential targets for future treatments. This research could lead to a better understanding of the disease and pave the way for new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of hereditary pancreatitis or those diagnosed with the condition.
Not a fit: Patients without a genetic predisposition to hereditary pancreatitis or those with unrelated pancreatic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that significantly improve outcomes for patients with hereditary pancreatitis.
How similar studies have performed: Previous research has shown promise in understanding genetic conditions through animal models, suggesting that this approach could yield valuable insights.
Where this research is happening
JACKSONVILLE, UNITED STATES
- MAYO CLINIC JACKSONVILLE — JACKSONVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JI, BAOAN — MAYO CLINIC JACKSONVILLE
- Study coordinator: JI, BAOAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.