Understanding the causes of heavy drinking and alcohol use disorder in adolescents

Determining the Contributions of Four AARDoC Functional Domains to the Etiology of Heavy Drinking and AUD Symptoms: A Prospective, Multimodal Approach

NIH-funded research University of Iowa · NIH-10917364

This study is looking at why some teens and young adults drink heavily and struggle with alcohol use, and it involves 480 participants aged 12-20 to help find better ways to support those who need it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10917364 on NIH RePORTER

What this research studies

This research investigates the various underlying causes of heavy drinking and alcohol use disorder (AUD) symptoms in adolescents and young adults. By enrolling 480 participants aged 12-20 who are at risk for heavy drinking, the study aims to identify how different neuro-behavioral factors contribute to these issues. The approach involves a longitudinal design, allowing researchers to track changes over time and better understand the complexities of AUD. This could lead to more personalized and effective treatment options for those affected.

Who could benefit from this research

Good fit: Ideal candidates for participation are adolescents and young adults aged 12-20 who are at risk for heavy drinking.

Not a fit: Patients who are not within the age range of 12-20 or do not exhibit elevated risk for heavy drinking may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved, tailored treatments for adolescents struggling with heavy drinking and alcohol use disorder.

How similar studies have performed: Previous research has shown promise in understanding the etiology of alcohol use disorders, but this specific multimodal approach is relatively novel.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Behavior-Related Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.