Understanding the causes of frequent asthma attacks in children
Official title: Pathogenesis of frequent asthma exacerbators
Funded at Cincinnati Childrens Hosp Med Ctr · NIH-10995701 · Data updated 2026-11-12
This study is looking at kids who have asthma attacks that land them in the hospital more than twice a year to find out what makes their asthma different, with the hope of discovering better treatments just for them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | September 7, 2024 |
| Project end | September 6, 2027 |
| Funding year | 2024 |
| Award (this year) | $41,915 |
| NIH project number | 1F30HL172613-01A1 |
| Project ID | NIH-10995701 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children who have been hospitalized for asthma exacerbations at least twice in the past year.
✕Less likely to help
Patients who do not have a history of frequent asthma exacerbations or who are not within the pediatric age group may not benefit from this research.
What this research studies
This research investigates the biological differences in children who frequently experience asthma exacerbations, specifically those who are hospitalized two or more times a year. By utilizing the Ohio Pediatric Asthma Repository, the study collects clinical data and biosamples from patients at major pediatric medical centers. The goal is to identify distinct biological markers associated with this specific asthma endotype, which could lead to more tailored and effective treatments for affected children.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for children with frequent asthma attacks, enhancing their quality of life.
How similar studies have gone: Previous research has shown promise in identifying distinct asthma endotypes, suggesting that this approach could yield valuable insights into treatment options.
Where this research is happening
-
Cincinnati Childrens Hosp Med Ctr
Cincinnati, United States Active
Researchers
- Principal investigator: Phelan, Kieran — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Phelan, Kieran
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.