Understanding the causes of early pulmonary fibrosis
Disease Mechanisms of Early Pulmonary Fibrosis
This study is looking for new ways to help people at risk of progressive pulmonary fibrosis by understanding how lung injuries can lead to the disease, so it can find ways to prevent symptoms before they start.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10846182 on NIH RePORTER |
What this research studies
This research aims to develop new therapies to significantly reduce the health impacts of progressive pulmonary fibrosis (PF). It focuses on understanding PF as a result of long-term lung injury rather than just a final stage of the disease. By studying genetic, metabolic, and environmental factors that contribute to the early stages of PF, the research seeks to identify ways to prevent the onset of symptoms. The program will utilize data from a cohort of asymptomatic relatives of patients with familial PF to inform its findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include asymptomatic individuals with a family history of pulmonary fibrosis.
Not a fit: Patients who already exhibit symptoms of pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative strategies for preventing pulmonary fibrosis before it becomes symptomatic.
How similar studies have performed: Previous research has shown promise in understanding disease mechanisms in similar conditions, suggesting potential for success in this novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Blackwell, Timothy S. — University of Michigan at Ann Arbor
- Study coordinator: Blackwell, Timothy S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.