Understanding the causes of delayed sleep-wake phase disorder

Physiological and Behavioral Basis of Circadian Rhythm Delayed Sleep-Wake Phase Disorder

NIH-funded research Northwestern University at Chicago · NIH-10937779

This study is looking at a sleep condition called Delayed Sleep-Wake Phase Disorder (DSWPD) to better understand how different types of it respond to light and sleep, so we can find more accurate ways to diagnose and treat people who have trouble sleeping at night and waking up in the morning.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10937779 on NIH RePORTER

What this research studies

This research investigates Delayed Sleep-Wake Phase Disorder (DSWPD), a condition where individuals struggle to fall asleep at night and wake up in the morning, impacting their daily lives. The study aims to differentiate between two subtypes of DSWPD based on their physiological responses to light and sleep patterns. By using advanced techniques like pupillometry, researchers will explore how these differences affect diagnosis and treatment options. The goal is to improve diagnostic accuracy and develop personalized treatment strategies for those affected by this disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who experience symptoms of delayed sleep-wake phase disorder.

Not a fit: Patients who do not have delayed sleep-wake phase disorder or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatments for individuals suffering from DSWPD, improving their sleep quality and overall well-being.

How similar studies have performed: Previous research has shown promising results in understanding circadian rhythm disorders, indicating that this approach may lead to significant advancements in treatment.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiometabolic DiseaseCardiometabolic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.