Understanding the causes of coronary microvascular disease
Mechanisms of Coronary Microvascular Disease
['FUNDING_OTHER'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10849847
This study is looking at how coronary microvascular disease affects heart blood flow in people with stable angina who have normal arteries, and it aims to find easier ways to diagnose this condition and understand how certain factors contribute to it, so we can help improve treatment for those affected.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10849847 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind coronary microvascular disease, which affects blood flow in the heart without the presence of obstructive coronary artery disease. It focuses on patients with stable angina who have normal coronary arteries but still experience ischemia. The study aims to identify non-invasive measures for diagnosing microvascular disease and to explore how factors like endothelial dysfunction and platelet interactions contribute to this condition. By analyzing these mechanisms, the research seeks to improve understanding and treatment options for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing stable angina with non-obstructive coronary artery disease.
Not a fit: Patients with obstructive coronary artery disease or those without symptoms of angina may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients suffering from coronary microvascular disease.
How similar studies have performed: Previous research has indicated that understanding microvascular dysfunction can lead to significant advancements in cardiovascular care, suggesting potential for success in this area.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SMILOWITZ, NATHANIEL ROSSO — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: SMILOWITZ, NATHANIEL ROSSO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.