Understanding the causes of cleft palate
Transcriptome and Network Analysis of Cleft Palate
This study is looking into how genes work together to cause cleft palate, a common birth defect, to help find better ways to diagnose and treat it for those who are affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11005530 on NIH RePORTER |
What this research studies
This research investigates the complex biological processes involved in the development of cleft palate, a common birth defect. By analyzing gene expression and biological networks, the study aims to uncover how various genes and signaling pathways interact during palatogenesis. This could lead to better diagnostic methods and treatment options for affected individuals. The research combines insights from both human and mouse studies to create a comprehensive understanding of the condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with cleft palate or those at risk of developing this condition.
Not a fit: Patients with cleft palate who are already receiving optimal treatment may not see additional benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for individuals with cleft palate.
How similar studies have performed: Previous research has shown promise in understanding genetic factors related to cleft palate, but this approach aims to provide a more integrated view of the biological processes involved.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Jabs, Ethylin Wang — Mayo Clinic Rochester
- Study coordinator: Jabs, Ethylin Wang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.