Understanding the causes of cervical glandular neoplasias
Investigations Into The Molecular Pathogenesis Of Cervical Glandular Neoplasias
This study is looking into how HPV infections lead to cervical adenocarcinoma, a type of cervical cancer that’s hard to screen for, to help find better ways to prevent and treat it for patients like you.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10884508 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind cervical adenocarcinoma, a type of cervical cancer that cannot be effectively screened for like other forms. It focuses on the role of HPV infections and how they contribute to the development of this cancer. By analyzing viral methylation patterns and host gene expression in affected tissues, the study aims to uncover critical insights that could lead to better prevention strategies. Patients may benefit from improved screening and treatment options based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include women diagnosed with cervical adenocarcinoma or those at high risk for developing this type of cancer.
Not a fit: Patients with squamous cell carcinoma or those without any cervical neoplasia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced prevention and treatment strategies for cervical adenocarcinoma, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promising results in understanding HPV-related cancers, indicating that this approach may yield valuable insights.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Burk, Robert D — Albert Einstein College of Medicine
- Study coordinator: Burk, Robert D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.