Understanding the causes of birth defects to improve prevention strategies

Comp A: Texas BD-STEPS III Core

NIH-funded research University of Texas Hlth Sci Ctr Houston · NIH-10907390

This study is looking into what causes birth defects to help prevent them, especially focusing on families with Mexican American backgrounds, so we can better understand and reduce these issues for all babies.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10907390 on NIH RePORTER

What this research studies

This research aims to investigate the factors that contribute to birth defects, which are significant causes of infant mortality and healthcare costs in the U.S. By analyzing data from a large birth defects registry, the project seeks to identify parental and infant determinants that may lead to these conditions. The study will focus on increasing diversity in its participant pool, particularly among Mexican Americans, to ensure a comprehensive understanding of the issue. The findings could help develop effective population-level prevention strategies to reduce the incidence of birth defects.

Who could benefit from this research

Good fit: Ideal candidates for participation include expectant parents and families with a history of birth defects, particularly those from diverse backgrounds, including Mexican Americans.

Not a fit: Patients who do not have a history of birth defects or are not expecting children may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies that reduce the occurrence of birth defects and associated health complications.

How similar studies have performed: Previous research in birth defects prevention has shown success in identifying risk factors and developing strategies, indicating that this approach has the potential for meaningful contributions to the field.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.