Understanding the causes of Avoidant/Restrictive Food Intake Disorder in adults
Neurobiological Underpinnings of Avoidant/Restrictive Food Intake Disorder in Adults
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10907742
This study is looking at how the brain and hormones affect adults aged 18-45 with Avoidant/Restrictive Food Intake Disorder (ARFID) to help us understand why some people struggle with eating and how it impacts their health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10907742 on ClinicalTrials.gov |
What this research studies
This research investigates the neurobiological factors contributing to Avoidant/Restrictive Food Intake Disorder (ARFID) in adults, a condition that can lead to significant weight loss and nutritional deficiencies. The study will involve a cohort of adults aged 18-45 with ARFID and healthy controls, examining hormonal responses and brain activity in relation to food cues. By utilizing a multidisciplinary approach, the research aims to uncover the underlying mechanisms of ARFID, focusing on aspects such as fear of aversive consequences and regulatory dysfunction. Participants will undergo assessments that include hormonal measurements and brain imaging to better understand their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18-45 who have been diagnosed with Avoidant/Restrictive Food Intake Disorder.
Not a fit: Patients outside the age range of 18-45 or those without ARFID may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for adults suffering from ARFID.
How similar studies have performed: While research on ARFID is limited, similar studies investigating the neurobiological aspects of eating disorders have shown promising results.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: THOMAS, JENNIFER JOANNE — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: THOMAS, JENNIFER JOANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.