Understanding the causes of aggressive prostate cancer in African American men
Official title: Molecular Determinants of Lethal Prostate Cancer in African-Americans
Funded at Howard University · NIH-11011783 · Data updated 2026-11-12
This study is looking at why African American men are more likely to have aggressive prostate cancer, by examining their genetic information to find clues that could help predict how the disease will progress, with the goal of improving treatment options for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Howard University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | September 20, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $190,014 |
| NIH project number | 1U54CA295337-01 |
| Project ID | NIH-11011783 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American men diagnosed with prostate cancer, particularly those with locally metastatic disease.
✕Less likely to help
Patients who are not of African descent or those with non-metastatic prostate cancer may not benefit from this research.
What this research studies
This research investigates the biological factors that contribute to the higher rates of aggressive prostate cancer in African American men compared to other populations. By analyzing genomic and epigenomic profiles of prostate cancer in this group, the study aims to identify specific molecular biomarkers that could predict disease outcomes. The research will involve creating a unique cohort of African American men with locally metastatic prostate cancer to better understand the differences between primary and metastatic disease. This approach seeks to address significant health disparities and improve personalized treatment options for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to the development of targeted therapies and improved prognostic tools for African American men with prostate cancer.
How similar studies have gone: Previous research has shown promising results in identifying biomarkers in other populations, but this specific focus on African American men is relatively novel.
Where this research is happening
-
Howard University
Washington, United States Active
Researchers
- Principal investigator: Hudson, Tamaro Syton — Howard University
- Study coordinator: Hudson, Tamaro Syton
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.