Understanding the causes of Adult T-cell leukemia/lymphoma
Pathophysiology of Adult T-cell leukemia/lymphoma
This study is looking at Adult T-cell leukemia/lymphoma, a tough cancer that often hits young adults, especially veterans, to find out why some patients don’t respond well to treatment and how we can make those treatments better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rlr VA Medical Center NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11098413 on NIH RePORTER |
What this research studies
This research investigates Adult T-cell leukemia/lymphoma (T-ALL), a severe form of cancer that often affects young adults, particularly veterans. The focus is on understanding the underlying mechanisms that lead to treatment resistance and relapse in patients. By studying specific cancer cells that survive chemotherapy, the research aims to identify new therapeutic targets to improve treatment outcomes. The approach includes biochemical characterization of key oncogenes involved in the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with T-cell acute lymphoblastic leukemia, particularly those who have experienced treatment resistance.
Not a fit: Patients with other types of leukemia or those who do not have T-cell acute lymphoblastic leukemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for Adult T-cell leukemia/lymphoma, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in targeting similar oncogenes in other aggressive leukemias, suggesting that this approach may be effective.
Where this research is happening
Indianapolis, United States
- Rlr VA Medical Center — Indianapolis, United States (Active)
Researchers
- Principal investigator: Dave, Utpal P — Rlr VA Medical Center
- Study coordinator: Dave, Utpal P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.