Understanding the causes and treatments for thoracic aortic aneurysm
Pharmacological Mechanistic Insights into Thoracic Aortic Aneurysm
['FUNDING_CAREER'] · UNIVERSITY OF KENTUCKY · NIH-11003314
This study is looking into how thoracic aortic aneurysms develop in people with Marfan syndrome, with the goal of finding new ways to treat this condition, and it's being led by Dr. Mary Sheppard at the University of Kentucky.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KENTUCKY (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-11003314 on ClinicalTrials.gov |
What this research studies
This research focuses on exploring the mechanisms behind thoracic aortic aneurysms, particularly in patients with Marfan syndrome. Led by Dr. Mary Sheppard at the University of Kentucky, the project aims to identify new therapeutic targets through preclinical research. The approach includes studying animal models to better understand the disease and develop effective treatments. The research is supported by a team of experts in various fields related to aortic health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with thoracic aortic aneurysm, especially those with Marfan syndrome.
Not a fit: Patients with aortic aneurysms not related to Marfan syndrome or those with advanced aortic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from thoracic aortic aneurysms.
How similar studies have performed: Previous research has shown promise in understanding aortic aneurysms through similar mechanistic approaches, indicating potential for success in this area.
Where this research is happening
LEXINGTON, UNITED STATES
- UNIVERSITY OF KENTUCKY — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHEPPARD, MARY BURCHETT — UNIVERSITY OF KENTUCKY
- Study coordinator: SHEPPARD, MARY BURCHETT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.