Understanding the causes and shared risks of chronic pain conditions

PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization

NIH-funded research Boston University Medical Campus · NIH-11080979

This study is looking at how different types of chronic pain, like back pain and migraines, are connected and what causes them, so we can find better ways to help people manage their pain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11080979 on NIH RePORTER

What this research studies

This research investigates the common mechanisms behind various chronic pain conditions affecting adults, such as back pain and migraines. By studying community-based cohorts, the research aims to identify shared risk factors and biological signals that contribute to chronic pain. The approach includes assessing pain sensitization through quantitative sensory testing, which may reveal underlying nervous system dysfunction. The goal is to improve pain management strategies by understanding how different pain conditions are interconnected.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who experience chronic pain conditions, regardless of their specific diagnosis.

Not a fit: Patients with acute pain conditions or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better treatment options for individuals suffering from chronic pain by addressing the root causes rather than just the symptoms.

How similar studies have performed: Previous research has shown promise in understanding chronic pain through similar approaches, indicating potential for significant advancements in treatment.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.