Understanding the causes and characteristics of substance use disorders
Official title: Elucidating phenotype and etiology of substance use disorders via integrative analysis of multi-dimensional datasets
Funded at Old Dominion University · NIH-10579580 · Data updated 2026-11-12
This study is looking at the different reasons people might struggle with substance use disorders, using a mix of genetic, environmental, and health information, to help find better ways to prevent and treat these issues.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Old Dominion University NIH-funded |
| Lab location | 1 site (Norfolk, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $462,378 |
| NIH project number | 1R15DA055906-01A1 |
| Project ID | NIH-10579580 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with substance use disorders, particularly those with varying clinical presentations and backgrounds.
✕Less likely to help
Patients who do not have substance use disorders or those with conditions unrelated to SUDs may not benefit from this research.
What this research studies
This research investigates the complex factors contributing to substance use disorders (SUDs) by analyzing various data types, including genetic, environmental, and clinical information. It aims to refine the understanding of different SUD phenotypes and their underlying causes, which can lead to better prevention, diagnosis, and treatment strategies. By employing advanced machine learning techniques, the study will integrate and analyze large datasets to uncover hidden patterns and associations that traditional methods may overlook.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for individuals suffering from substance use disorders.
How similar studies have gone: Previous research using integrative data analysis has shown promise in uncovering genetic and environmental factors related to various disorders, suggesting that this approach could yield valuable insights for substance use disorders as well.
Where this research is happening
-
Old Dominion University
Norfolk, United States Active
Researchers
- Principal investigator: Sun, Jiangwen — Old Dominion University
- Study coordinator: Sun, Jiangwen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.