Understanding the brain's role in persistent breathing difficulties
Characterizing the Sensory and Affective Neural Components of Persistent Dyspnea
This study is looking at how different parts of the brain affect breathing and cause ongoing breathlessness, aiming to find new ways to help people with chronic breathing problems feel better by focusing on the brain instead of just the lungs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10848353 on NIH RePORTER |
What this research studies
This research investigates how higher-level brain structures influence breathing and contribute to persistent dyspnea, a condition where patients experience significant discomfort in breathing. By examining the neural pathways involved, the study aims to uncover the complex interactions between brain regions and the brainstem that regulate respiration. The research utilizes a model of dyspnea to better understand the symptoms and develop potential treatments that target the brain rather than just the lungs. This approach is particularly relevant for patients with chronic respiratory diseases where traditional treatments may not be effective.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing persistent dyspnea due to conditions like COPD, asthma, or other chronic respiratory diseases.
Not a fit: Patients with reversible respiratory conditions or those not experiencing significant breathing discomfort may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from persistent dyspnea, improving their quality of life.
How similar studies have performed: Other research has shown promising results in understanding the brain's influence on respiratory function, indicating that this approach has potential for success.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Herrero Rubio, Jose Luis — Feinstein Institute for Medical Research
- Study coordinator: Herrero Rubio, Jose Luis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.