NIH-funded research R01 grant

Understanding the brain's role in alcohol use disorders and suicide among American Indians

Official title: Neural Basis of alcohol/substance use disorders and suicide in American Indians

Funded at Scripps Research Institute, the · NIH-10559631 · Data updated 2026-11-12

This study is looking at how brain function and community factors affect alcohol use and suicidal thoughts in American Indian communities, and it’s for people who want to help improve health and support for their communities.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionScripps Research Institute, the
NIH-funded
Lab location1 site (La Jolla, United States)
Project startFebruary 5, 2019
Project endSeptember 30, 2025
Funding year2023
Award (this year)$615,329
NIH project number5R01AA027316-05
Project IDNIH-10559631 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include American Indian individuals, both teens and adults, who are experiencing alcohol use disorders or suicidal thoughts.

Less likely to help

Patients who do not identify as American Indian or who do not have issues related to alcohol use or suicidal behaviors may not benefit from this research.

What this research studies

This research investigates the neural mechanisms and risk factors associated with alcohol use disorders and suicidal behaviors in American Indian communities. By focusing on both individual and community-level influences, the study aims to uncover the biological and psychological factors that contribute to these issues. Participants will be involved in assessments that may include interviews, surveys, and biological measures to gather comprehensive data. The goal is to address significant health disparities faced by American Indians and provide insights that could lead to better prevention and treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for alcohol use disorders and suicide prevention in American Indian populations.

How similar studies have gone: While there is limited research specifically targeting American Indian populations, studies in other ethnic groups have shown success in identifying similar neural and psychological factors related to substance use and suicide.

Where this research is happening

  • Scripps Research Institute, the
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Ehlers, Cindy L — Scripps Research Institute, the
  • Study coordinator: Ehlers, Cindy L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.