Understanding the brain mechanisms behind opioid addiction.

Integrative Omics Center for Accelerating Neurobiological Understanding of Opioid Addiction (ICAN)

NIH-funded research Research Triangle Institute · NIH-11170220

This study is looking at how opioid addiction affects the brain by examining different biological factors, and it aims to find better ways to help people struggling with this issue.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11170220 on NIH RePORTER

What this research studies

This research focuses on exploring the neurobiological aspects of opioid addiction through an integrative approach that combines various omics technologies. By analyzing genetic, proteomic, and metabolomic data, the project aims to uncover the underlying mechanisms that contribute to opioid dependence. Patients may benefit from insights gained into how opioids affect the brain, potentially leading to improved treatment strategies. The research will involve collaboration among experts in neuroscience, genetics, and addiction studies to ensure a comprehensive understanding of the condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are currently experiencing opioid addiction or dependence.

Not a fit: Patients who are not affected by opioid addiction or those who have not used opioids may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for individuals struggling with opioid addiction.

How similar studies have performed: Other research has shown promise in using integrative omics approaches to understand addiction, suggesting that this methodology could yield valuable insights.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.