NIH-funded research NIH-funded research

Understanding the brain circuits that control facial movements

Official title: Neuroanatomical and molecular architecture of high- and low-level circuits controlling orofacial movements

Funded at University of California, San Diego · NIH-10930310 · Data updated 2026-11-12

This study is looking at how different parts of the brain work together to control movements we use for eating, breathing, and talking, and it aims to help us understand how these processes can be affected by different health conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startAugust 15, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$396,323
NIH project number1U19NS137920-01
Project IDNIH-10930310 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with disorders that impair orofacial movements, such as neurological conditions or injuries.

Less likely to help

Patients with conditions unrelated to motor control or orofacial movements may not benefit from this research.

What this research studies

This research investigates the complex brain circuits that manage orofacial movements, which are essential for activities like eating, breathing, and communication. By examining both high-level and low-level circuits in the brain, the project aims to uncover how these circuits interact to produce precise motor actions. The study employs advanced techniques such as viral genetic tracing and whole-brain imaging to map the anatomical and molecular architecture of these circuits. This research could provide insights into how motor control is organized in the brain and how it can be affected by various conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for conditions affecting facial and motor control.

How similar studies have gone: Other research has shown success in mapping brain circuits related to motor control, suggesting that this approach has potential for meaningful discoveries.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Economo, Michael Nicholas — University of California, San Diego
  • Study coordinator: Economo, Michael Nicholas

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.